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中科院院士支志明應邀作“藥學前沿承嘏講壇”第二十一講

文章來源:上海藥物研究所   發布時間:2019-04-22  【字號:     】  

  4月18日下午,中國科學院上海藥物研究所“藥學前沿承嘏講壇”第二十一講在承嘏廳舉行。中科院院士、香港大學周光召基金教授支志明應邀作了題為“Anti-cancer Medicines”的專題報告。中科院院士、上海藥物所研究員岳建民主持報告會,上海藥物所二百余位科研人員和研究生參加本次報告。

  癌癥已成為致死率位居全球第二的疾病。目前治療癌癥的手段主要包括手術、化療及放療,但是化療和放療都會對機體造成不同程度的副作用。支志明在報告中主要講了三種抗癌藥物的研究進展,分別是金屬鉑類化合物、金類化合物以及傳統中藥中可用于抗癌的藥物。他重點介紹了其課題組設計合成的利用N-雜卡賓作配體的鉑和金類抗癌藥物及金卟啉類抗癌化合物,通過體內和體外生物實驗對新設計化合物的藥效分別進行了考查,并進行了化合物在體內作用靶點的驗證。

  支志明還分享了中藥應用于癌癥治療的案例,例如知母皂苷TA-III具有抗癌及治療阿爾茨海默癥的功效。支志明的報告內容新穎豐富、視角獨特準確、分析理性透徹,現場座無虛席。會后,研究人員就抗癌藥物相關問題同他進行了熱烈探討,中科院院士陳凱先、岳建民共同為支志明頒發了講壇證書。

  支志明現為香港大學周光召基金教授,1995年當選為中國科學院院士,2013年當選美國科學院外籍院士。曾獲國家自然科學一等獎、英國皇家化學學會百周年獎、中國化學會黃耀曾金屬有機化學終身成就獎及Ryoji Noyori ACES獎等。發表學術論文超過950篇,H指數高達112,被美國科學資訊研究所(ISI)列入最高引用率學者。

  本期講壇由上海藥物所主辦、新藥研究國家重點實驗室和中科院受體結構與功能重點實驗室聯合承辦。

 

支志明作報告 

 

上海藥物所師生參加專題報告會 

 

陳凱先和岳建民共同為支志明頒發講壇證書 




(責任編輯:葉瑞優)

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